AREDS-2 : Beta-Carotene-Free AREDS formula plus Lutein and Zeaxanthin MacuSave is formulated with the highest quality ingredients to maintain the maximum purity and potency. MacuSave provides vision protecting clinically recommended AREDS-2 formula without beta-carotene with the addition of Luetin and Zeaxanthin in two easy to swallow capsules per day. For individuals with swallowing difficulty MacuSave capsules may be opened into food or drink.
Product Highlights
Suggested Use: One capsule twice daily with meal. Note:
Made in USA from the finest quality and most bio-available ingredients. Physician recommended. Your satisfaction always guaranteed. MacuSave is available directly from Foundation for Saving Sight MacuSave can be ordered by calling Toll Free: 1-855-AMD-HELP or by visiting FoundationForSavingSight.org
Who should take MacuSave? If you are a smoker or very recent ex-smoker at high risk for developing advanced AMD, you should consider taking MacuSave. MacuSave is formulated for smokers or very recent ex-smokers as it provides a beta-carotene-free formula recommend by AREDS clinical trial with additional protective effect of Lutein and Zeaxanthin. Your eye care professional can tell you if you have Macular Degeneration and if you are at risk for developing the advanced form of this disease. Treatment of at-risk patients with formulation such as MacuSave is now considered standard of care. It is important to talk with your doctor before taking these high levels of vitamins and minerals. Why Beta-Carotene free formula? Large clinical trials sponsored by the National Cancer Institute demonstrated that beta-carotene may increase the risk of lung cancer in current heavy smokers.Therefore, with this information in mind, Foundation For Saving Sight has made MacuSave conveniently available for smokers or recent ex-smokers. MacuSave proovides clinically recommended AREDS-2 formula with no Beta-Carotene. In deciding whether to include beta-carotene in your formulation, we highly advise you and your doctor to balance the apparent increase in the risk of lung cancer associated with beta-carotene with the risk of Macular Degeneration progression.
Where are MacuSave products made?
MacuSave Products are made in facilities within the US. All facilities have been certified with “A” ratings under the NPA (formerly NNFA) Good Manufacturing Practices (NPA GMP) program. The NPA GMP and NSF GMP programs require an independent audit of our facilities, procedures, training, sanitation, and personnel. These regulatory requirements provide guidelines for necessary processes, procedures, and documentation to assure the product produced has the identity, strength, composition, quality and purity it is represented to possess. State-of-the-art packaging and laboratory facilities are also registered with US Food & Drug Administration as a drug establishment, licensed to process ethical and over-the-counter pharmaceutical products.
What is the AREDS? The Age-Related Eye Disease Study (AREDS) is a major clinical trial sponsored by the National Eye Institute (NEI), one of the federal government's National Institutes of Health (NIH). This study had two objectives. One, to learn more about the natural history and risk factors of age-related macular degeneration (AMD) and cataracts. Secondly, to evaluate the effect of high doses of antioxidants and zinc (such as MacuSave) on the progression of AMD and cataracts. Results from the AREDS showed that high levels of antioxidants and zinc significantly reduce the risk of advanced age-related macular degeneration (AMD) and its associated vision loss. This finding is of great public health importance, since the incidence of AMD is expected to triple by the year 2025. Treatment of at-risk patients with the AREDS formulation such as MacuSave is now considered standard of care
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What is “AREDS-2”?
Researchers with the Age-Related Eye Disease Study (AREDS) reported in 2001 that a nutritional supplement called the AREDS formulation can reduce the risk of developing advanced age-related macular degeneration (AMD). The original AREDS formulation contains vitamin C, vitamin E, beta-carotene, zinc and copper.
In 2006, the same research group, which is based at NIH's National Eye Institute, began a second study called AREDS2 to determine if they could improve the AREDS formulation. They tried adding omega-3 fatty acids, as well as the antioxidants lutein and zeaxanthin, which are in the same family of nutrients as beta-carotene. The researchers also tried substituting lutein and zeaxanthin for beta-carotene, which prior studies had associated with an increased risk of lung cancer in smokers. The study found that while omega-3 fatty acids had no effect on the formulation, lutein and zeaxanthin together appeared to be a safe and effective alternative to beta-carotene.
Can a Daily Multivitamin Alone Provide the Same High Levels of Antioxidants and Zinc as MacuSave? No. MacuSave levels of antioxidants and zinc are considerably higher than the amounts in any daily multivitamin. These levels are based on recommendation by AREDS formulation's. Can Diet Alone Provide the Same High Levels of Antioxidants and Zinc as MacuSave? No. The high levels of vitamins and minerals are difficult to achieve from diet alone. However, based on studies it is always recommend that patients who have been diagnosed with Macular Degeneration to have diets rich in green, leafy vegetables so that they have a lower risk of progression of AMD. What About Lutein and Zeaxanthin? Lutein is a carotenoid found in dark leafy green vegetables. Carotenoids are concentrated in the macula, the part of the eye responsible for central vision. Studies suggest that Lutein plays an essential role in maintaining healthy central vision by protecting against free radical damage and filtering blue light. Why MacuSave through Foundation for Saving Sight?
AREDS Finds High Dose Antioxidants and Zinc Slow AMD Progression.
AREDS Analysis: Higher Lutein Intake Linked to AMD Risk Reduction.
AMD Risk Reduction with Higher Lutein Consumption.
Lutein Supplements Restore Macular Pigment Density in AMD.
Serum Levels of Lutein Correlate with Macular Pigment Density.
Stable Intake of Lutein and Zeaxanthin Reduces AMD Risk in Women.
Supplemental Lutein Clnically Improves Vision Parameters in AMD.
